Browsing by Author "Ayan, Meral"
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The neural gamma(2)alpha(1)beta(2)alpha(1)beta(2) gamma amino butyric acid ion channel receptor: structural analysis of the effects of the ivermectin molecule and disulfide bridges
Ayan, Meral; Eşsiz, Şebnem (Springer, 2018)While similar to 30% of the human genome encodes membrane proteins only a handful of structures of membrane proteins have been resolved to high resolution. Here we studied the structure of a member of the Cys-loop ligand ... -
Structural study of gaba type a receptor : the effect of intrasubunit disulphide bridges on dynamics
Ayan, Meral (Kadir Has Üniversitesi, 2014)In the mammalian brain the gamma-aminobutyric acid type A receptor is the most commonly expressed subtype of receptor family. Although there is a rich pharmacological activity of R, specific molecular features are still ...